The quality concept comprises:
- internal process control
- ring trials
- determination of user satisfaction
During ring trials, biomaterial samples are sent from reference laboratories to the participating biobanks. Upon arrival, the biosamples are processed according to the respective operating procedures of the biobank, starting with the reception to the storage of the samples. After a defined storage time, the prepared samples are sent to a reference laboratory in order to analyse the sample for various parameters.
This approach allows an evaluation of the process quality (by determining the sample quality) starting from sample reception and storage through to production and measurement of derivatives.
By means of a literature review, pre-analytical quality biomarkers are identified that are to be analysed in a GBA biobank. Considering the entire process chains, these are evaluated in relation to quality targets to generate “key figures” from them. These should contribute to the monitoring, and if necessary, improvement of the processes.